POTENTIAL ANTICANCER AGENTS III. URETHANE-TYPE NITROGEN MUSTARDS OF SOME SYNTHETIC ESTROGENS

I Niculescu-Duvăz, V Feyns, E Grant…

文献索引：Niculescu-Duvaz,I. et al. Canadian Journal of Chemistry, 1966 , vol. 44, p. 1102 - 1105

全文：HTML全文

被引用次数: 3

摘要

While studying the anticancer activity of the urethane-type nitrogen mustards, n:e prepared a nuillber of conlpounds of this type fro111 synthetic estrogens, with the purpose of establishing a relationship between the estrogenic activity of the bis-hydroxyphenyl derivatives and the anticancer action of their nitrogen mustard carban~ates. Since com- pounds I and I1 that had previously been prepared (I) exhibited 50-60y0 inhibitions on Walker carcinosarco~na 256 (2), it ...