Summary Application has been made of Einhorn's amidomethylation procedure to nitroveratrole and several acylated 2-nitro-4, 5-dimethoxybenzyl-amines prepared. Some of these can be directly converted to quinazoline derivatives by reduction. Hydrolysis of them yields 2-nitro-4, 3-dimethoxybenzylamine, which can be reduced to 2-amino-4, 5- dimethoxybenzylamine, and this, in turn, can be converted to 617-dimethoxyquinazoline ...
[Klaerner, Frank-Gerrit; Krawczyk, Bernd; Ruster, Volker; Deiters, Ulrich K. Journal of the American Chemical Society, 1994 , vol. 116, # 17 p. 7646 - 7657]