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The synthesis of peptides related to gramicidin S

BF Erlanger, H Sachs, E Brand

文献索引:Erlanger et al. Journal of the American Chemical Society, 1954 , vol. 76, p. 1806,1809

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被引用次数: 68

摘要

We are reporting the synthesis of a decapeptide having the sequence and configurations of amino acids believed to exist in gramicidin S. Consden, Gordon, Martin and Synge3 have determined the sequence of the five different amino acid residues of gramicidin S to be4:-Val- Om-Leu-Phe-Pro-(LLLDL). It has been established by Battersby and Craig5 that the molecular weight of gramicidin S is that of a decapeptide. Thus the sequence must appear ...