Room temperature ionic liquid promoted improved and rapid synthesis of 2, 4, 5-triaryl imidazoles from aryl aldehydes and 1, 2-diketones or α-hydroxyketone
An improved and rapid one-pot synthesis of 2, 4, 5-triaryl imidazoles in a room temperature ionic liquid is described, which does not need any added catalyst. Different ionic liquids based on 1-n-butyl and 1, 3-di-n-butyl imidazolium salts were screened and their efficacy in terms of acidity and polarity have been correlated with yields and reaction period. The one- pot methodology resulting in excellent isolated yields in short reaction times is ...
