A Versatile and Highly Efficient Method for 1??Chlorination of Terminal and Trialkylsilyl??Protected Alkynes

…, B Pigulski, M Charewicz, S Szafert

文献索引：Gulia, Nurbey; Pigulski, Bartlomiej; Charewicz, Marta; Szafert, Slawomir Chemistry - A European Journal, 2014 , vol. 20, # 10 p. 2746 - 2749

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被引用次数: 9

摘要

Abstract A highly efficient one-pot procedure for the preparation of 1-chloroalkynes and 1- chlorobutadiynes from terminal and trialkylsilyl-protected precursors is reported. This convenient reaction, proceeding under mild conditions, utilizes N-chlorosuccinimide as the chlorinating agent and tolerates a range of functional groups.