Journal of organometallic chemistry

Hydroboration–azide alkylation as efficient tandem reactions for the synthesis of chiral non racemic substituted pyrrolidines

A Salmon, B Carboni

文献索引：Salmon, Anne; Carboni, Bertrand Journal of Organometallic Chemistry, 1998 , vol. 567, # 1-2 p. 31 - 37

全文：HTML全文

被引用次数: 14

摘要

Pyrrolidines are an important class of five-membered heterocycles with remarkable biological properties [1]. In addition to pharmaceutical applications, the pyrrolidine moiety has also seen wide use as a chiral auxiliary for asymmetric synthesis [2]. Accordingly, development of efficient general methods for the preparation of chiral, non racemic pyrrolidines is of significant value and an increasing number of papers and reports recently appeared in the literature [3]. ...