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Synthetic studies toward mitomycins. 1. Total synthesis of deiminomitomycin A

F Nakatsubo, AJ Cocuzza, DE Keeley…

文献索引:Nakatsubo; Cocuzza; Keeley; Kishi Journal of the American Chemical Society, 1977 , vol. 99, # 14 p. 4835 - 4836

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被引用次数: 59

摘要

The mitomycins (la-e) are a class of antibiotics with activity against gram-positive and gram- negative bacteria and also against several kinds of tumors.'Since their structures were first elucidated in 1962, l numerous synthetic approaches to the mitomycins have been reported. 2 However, the mitomycins