Tetrahedron

Synthesis of polyfunctional indoles and related heterocycles mediated by cesium and potassium bases

…, W Dohle, AL Rodriguez, B Schmid, P Knochel

文献索引：Koradin, Christopher; Dohle, Wolfgang; Rodriguez, Alain L.; Schmid, Bertram; Knochel, Paul Tetrahedron, 2003 , vol. 59, # 9 p. 1571 - 1587

全文：HTML全文

被引用次数: 237

摘要

A general preparation of 2-substituted indoles starting from functionalized 2-alkynylanilines has been developed. This base mediated reaction has also been used to synthesize the heterocyclic core of the marine alkaloid hinckdentine A. Furthermore the reaction was successfully adapted to the solid phase. Benzofurans and isoindolones could also be prepared with this method.