Microwave irradiation promotes the rapid and efficient reaction of a thiophenol and aryl or heteroaryl halide using a copper or palladium catalyst and a range of ligands, depending upon substrate. Of particular utility is the use of copper (I) iodide (5 mol%) and trans- cyclohexane-1, 2-diol as ligand under basic conditions and microwave irradiation to give the corresponding sulfide in high yield. This method for C− S bond formation is applied in the ...
