2??, 3??and 4??[18F] Fluoropyridine by no??carrier??added nucleophilic aromatic substitution with K [18F] F??K222–a comparative study

M Karramkam, F Hinnen, F Vaufrey…

文献索引：Karramkam; Hinnen; Vaufrey; Dolle Journal of Labelled Compounds and Radiopharmaceuticals, 2003 , vol. 46, # 10 p. 979 - 992

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被引用次数: 48

摘要

Abstract Compared to homoaromatic and aliphatic nucleophilic radiofluorinations, only few references can be found in the literature describing nucleophilic substitutions with [18 F] fluoride ion of heteroaromatic compounds such as pyridines and only reactions involving fluorination processes at the ortho-position (2-position) have been more intensively studied. In the present paper, the scope of the nucleophilic aromatic fluorinations at the meta-and ...