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Synlett

Synthesis of Polycyclic Indolone and Pyrroloindolone Heterocycles via the Annulation of Indole-and Pyrrole-2-Carboxylate Esters with Arynes

RD Giacometti, YK Ramtohul

文献索引:Giacometti, Robert D.; Ramtohul, Yeeman K. Synlett, 2009 , # 12 p. 2010 - 2016

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被引用次数: 3

摘要

Polycyclic heterocycles containing indoles or pyrroles are interesting structural motifs present in a number of natural and unnatural products displaying a wide variety of biological and pharmacological properties. [¹] Construction of these polycyclic heterocycles, in particular those containing an aryl-N-indole or N-pyrrole bond, usually requires lengthy multiple-step syntheses involving transition-metal-catalyzed reactions. [²] Hence, the development of new, mild, and ...