Studies in the Imidazole Series. 100. Synthesis of Derivatives of Imidazo [1, 2-a] pyrimidine from 2-Aminopyrimidines, Methyl Aryl Ketones, and Halogens

…, IA Mazur, GK Rogul'chenko, EV Aleksandrova…

文献索引：Kochergin; Mazur; Rogul'chenko; Aleksandrova; Mandrichenko Chemistry of Heterocyclic Compounds, 2000 , vol. 36, # 12 p. 1437 - 1440

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摘要

Abstract We have synthesized imidazo [1, 2-a] pyrimidine derivatives by reaction of 2- aminopyrimidines with methyl aryl ketones and halogens (bromine, iodine). Using bromine leads to formation of 6-bromo-and 3, 6-dibromo-substituted 2-arylimidazo [1, 2-a] pyrimidines.