Journal of heterocyclic chemistry

Furopyridines. XXI. Synthesis of cyano derivatives of furo??[2, 3??b]??,??[2, 3??c]??and??[3, 2??c] pyridine and their conversion to derivatives having another carbon?? …

S Shiotani, K Taniguchi

文献索引：Shiotani, Shunsaku; Taniguchi, Katsunori Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 2 p. 493 - 499

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被引用次数: 9

摘要

Abstract Cyanation of furo [2, 3-b]-,-[2, 3-c]-and-[3, 2-c] pyridine N-oxides 1a, 1b and 1c by the Reissert-Henze method, reaction with benzoyl chloride and trimethylsilyl cyanide in dichloromethane and the reaction with trimethylsilyl cyanide and triethylamine in acetonitrile afforded 6-cyanofuro [2, 3-b]-2a, 7-cyanofuro [2, 3-c]-2b and 4-cyanofuro [3, 2-c] pyridine 2c in moderate to excellent yield. The cyano group in 2a, 2b and 2c was converted to ...