Journal of Organometallic Chemistry

An interesting chloride ion effect in the Heck reaction

CA Merlic, MF Semmelhack

文献索引：Merlic, Craig A.; Semmelhack, M.F. Journal of Organometallic Chemistry, 1990 , vol. 391, # 2 p. C23 - C27

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被引用次数: 34

摘要

In a typical reaction, 2 mmol aryl iodide, 3 mmol olefin, 3 mmol potassium carbonate, 3 mmol potassium chloride and 0.07 mmol palladium on carbon in 3 ml DMF were combined in a resealable pressure tube under argon and heated at 100°C until TLC indicated the consumption of aryl iodide. The reaction mixture was filtered through a short plug of silica gel with ethyl acetate, washed successively with water (4×) and brine, and dried (MgSO 4 ). The product was purified by ...