3-Amino-1, 2-benzisoxazoles: A new family of potent inhibitors of LTB 4 binding to the human neutrophils

H Suh, SJ Jeong, YN Han, HJ Lee, JH Ryu

文献索引：Suh, Hongsuk; Jeong, Soo-Jeong; Han, Yong Nam; Lee, Hwa-Jin; Ryu, Jae-Ha Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 4 p. 389 - 392

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被引用次数: 9

摘要

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A new family of 3-amino-1,2-benzisoxazoles was designed and synthesized to be a potent inhibitors of LTB 4 binding to the human neutrophils. HS-1141 appears to be one of the strongest inhibitors of LTB 4 binding reported so far (IC 50 =7nM). ... A new family of 3-amino-1,2- ...