Skipped (Z, Z) dienes and (Z&Z) trienes constitute a partial structure of many natural and/or bioactive compounds such as, for example, the polyunsaturated fatty acids and the arachidonic acid metabolites.'Different routes to these types of compounds or intermediates have been reportedlJ but they very often involve copper (I)-catalyzed allylic or propargylic substitution of halides or tosylates by acetylenic Grignard reagents followed by ...
