Scaling up of dihydropyridine ester synthesis by using aqueous hydrotrope solutions in a continuous microwave reactor

BM Khadilkar, VR Madyar

文献索引：Khadilkar, Bhushan M.; Madyar, Virendra R. Synthetic Communications, 1999 , vol. 29, # 7 p. 1195 - 1200

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被引用次数: 59

摘要

We report here the scaling up of clinically important dihydropyridine by using a continuous microwave reactor (CMR). We also report the use of aqueous hydrotrope solution as a cheap, safe and “green” alternative to organic solvent to carry out homogeneous reactions