Benefits of a Dual Chemical and Physical Activation: Direct aza-Michael Addition of Anilines Promoted by Solvent Effect under High Pressure

…, J Maddaluno, AY Rulev, J Legros

文献索引：Lebleu, Thomas; Ma, Xiaolu; Maddaluno, Jacques; Legros, Julien Chemical Communications, 2014 , vol. 50, # 15 p. 1836 - 1838

全文：HTML全文

被引用次数: 4

摘要

The unique combination of hexafluoroisopropanol (HFIP) employed as solvent and hyperbaric conditions (10–15 kbar) allows unprecedented 1, 4-addition of poor nucleophiles, such as aromatic amines, onto sluggish (cumbersome) Michael acceptors