Intermolecular Mizoroki–Heck Reaction of Aliphatic Olefins with High Selectivity for Substitution at the Internal Position

L Qin, X Ren, Y Lu, Y Li, JS Zhou

文献索引：Qin, Liena; Ren, Xinfeng; Lu, Yunpeng; Li, Yongxin; Zhou, Jianrong Angewandte Chemie - International Edition, 2012 , vol. 51, # 24 p. 5915 - 5919

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被引用次数: 46

摘要

The Mizoroki–Heck reaction generally refers to Pd-catalyzed CÀC bond formation between organic (pseudo) halides and olefins. Today, it has become a powerful tool to prepare substituted olefins.[1] A key issue in intermolecular Heck reactions is the control of the site where aryl groups insert into olefins. High regioselectivity can be easily achieved for olefins carrying substituents with a significant electronic difference at the two olefinic sites,[2] such ...