Synthesis of chiral 2-(4-phenoxyphenylsulfonylmethyl) thiiranes as selective gelatinase inhibitors

M Lee, MM Bernardo, SO Meroueh, S Brown…

文献索引：Takano, Seiichi; Seya, Kazuhiko; Goto, Emiko; Hirama, Michiyasu; Ogasawara, Kunio Synthesis, 1983 , # 2 p. 116 - 117

全文：HTML全文

被引用次数: 43

摘要

... The (R)-1 and (S)-1 enantiomers of compound 1 were each synthesized in this study and ... and the issue of enantioselectivity, we opted for the original route outlined in Scheme 2. ... Synthesis of (S)-1 was performed according to the same procedure, with the sole substitution of (S ...