7,8-fused disubstituted analogues of 1 possessed no noticeable desired activity. ... Introduction We have previously reported that a series of 4,5,6,7- tetrahydro-5-methylimidazo[4,5,l~~l[l,4lbenzodi ~epin- 2(W)-ones, 1, have been found to possess significant inhibitory activity against the human immunodeficiency virus type 1 (HIV-11.l To those following the progress of potential therapeutic agents to combat the HIV-1 virus, the causative infection of acquired immune deficiency ...
