Molecular pharmaceutics

RGD-based strategies to target alpha (v) beta (3) integrin in cancer therapy and diagnosis

F Danhier, AL Breton, V Préat

文献索引：Rerat, Vincent; Dive, Georges; Cordi, Alex A.; Tucker, Gordon C.; Bareille, Reine; Amedee, Joelle; Bordenave, Laurence; Marchand-Brynaert, Jacqueline Journal of Medicinal Chemistry, 2009 , vol. 52, # 22 p. 7029 - 7043

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被引用次数: 274

摘要

... Select a Journal or Book ... affinity, receptor selectivity, and other biological properties.(26) Linear RGD peptide proved highly susceptible to chemical degradation ... the amino acids (Phe) in the unnatural d-conformation (d-Phe) resulted in the cyclic peptide c(RGDfK) developed ...