The conversion of racemic terminal epoxides into either (+)-or (−)-diol γ-and δ-lactones

ZY Liu, JX Ji, BG Li

文献索引：Liu, Zhi-Yu; Ji, Jian-Xin; Li, Bo-Gang Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 20 p. 3519 - 3521

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被引用次数: 19

摘要

Hydrolytic kinetic resolution (HKR) as developed by Jacobsen's group 1 provided practical access to both terminal epoxides and 1,2-diols in excellent ee using (R,R)-(salen)Co(OAc) complex A as the catalyst and water as the only reagent. However, HKR afforded two kinds of compounds, epoxides and diols, with the opposite configuration and the two products have to be separated for further use in most cases. 2–5 Considering the advantages of ...