Many species of the genus Centaurea (Asteraceae) have been used in folk medcine since ancient times. These plants are generally rich in flavonoids and sesquiterpene lactones, which are the main constituents responsible for biological activity [1–6]. In a previous study, we described 10 flavonoids from Centaurea furfuracea [6, 7]. C. furfuracea Coss. et kral. was collected at the beginning of April 1992 in the region of Biskra and was identified by Dr. M. ...