Tetrahedron

Internal resin capture—A self purification method for the synthesis of C-terminally modified peptides

M Davies, M Bradley

文献索引：Davies, Michael; Bradley, Mark Tetrahedron, 1999 , vol. 55, # 15 p. 4733 - 4746

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被引用次数: 24

摘要

A synthetic strategy which allows for the general modification of peptides at the C-terminus has long been the goal of the synthetic chemist. We report here the full synthetic details of our inversion and modification methodology demonstrating the method with the synthesis of peptide amides, alcohols, nitriles and a range of other modified peptides.