A facile and efficient microwave-mediated S-alkylation of thiophosphates

LK Pandey, A Mazumder, U Pathak

文献索引：Pandey, Lokesh Kumar; Mazumder, Avik; Pathak, Uma Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2009 , vol. 48, # 4 p. 602 - 605

全文：HTML全文

被引用次数: 1

摘要

A convenient, highly efficient, safe microwave-mediated S-alkylation of O, O'-dialkyl thiophosphate has been reported. Clean and rapid S-alkylation of thiophosphates can be achieved by irradiating a mixture of dialkylthiophosphate salt and alkyl halide under microwave for a brief period. Alkylation occurs exclusively at sulfur to provide S-alkylated products. Through a simple workup, pure compounds have been obtained easily in good ...