Chemistry–A European Journal

Highly Chemoselective Calcium??Catalyzed Propargylic Deoxygenation

VJ Meyer, M Niggemann

文献索引：Meyer, Vera J.; Niggemann, Meike Chemistry - A European Journal, 2012 , vol. 18, # 15 p. 4687 - 4691

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被引用次数: 22

摘要

Abstract A calcium-catalyzed direct reduction of propargylic alcohols and ethers has been accomplished by using triethylsilane as a nucleophilic hydride source. At room temperature a variety of secondary propargylic alcohols was deoxygenated to the corresponding hydrocarbons in excellent yields. Furthermore, for the first time, a catalytic deoxygenation of tertiary propargylic alcohols was generally applicable. The same protocol was suitable for ...