Catalytic scaffolding ligands: an efficient strategy for directing reactions

TE Lightburn, MT Dombrowski…

文献索引：Lightburn, Thomas E.; Dombrowski, Michael T.; Tan, Kian L. Journal of the American Chemical Society, 2008 , vol. 130, # 29 p. 9210 - 9211

全文：HTML全文

被引用次数: 88

摘要

The design and application of a scaffolding ligand that promotes branch and diastereoselective hydroformylation of terminal olefins as well as the regio-and diastereoselective hydroformylation of disubstituted olefins is reported. It is shown that the ligand covalently and reversibly bonds to the substrate, allowing for directed hydroformylation. As the substrate ligand interaction is dynamic, hydroformylations are ...