Separation and stereochemical assignment of erythro and threo isomers of the m-nitro analog of (.+-.)-chloramphenicol

…, PN Nugara, EM Holt, KP Holland

文献索引：Hill, Richard K.; Nugara, Peter N.; Holt, Elizabeth M.; Holland, Kathleen P. Journal of Organic Chemistry, 1992 , vol. 57, # 3 p. 1045 - 1047

全文：HTML全文

被引用次数: 8

摘要

Chloramphenicol (l), the first of the broad-spectrum antibiotics, isolated from aerobic cultures of Streptomyces Venezuela more than 30 years ago, still finds application today in human and veterinary medicine for treatment of serious staphylococcus infections and is the only dependable medication for typhoid fever and Rocky Mountain spotted fever. It has also been used in treating many diseases in food-producing animals caused by Gram-negative ...