Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The first synthesis of nostoclide I (1a) and II (1b) has been accomplished in a concise, fully regio- and stereocontrolled manner by sequential 2,3,4-trisubstitution of butenolide (6) using 2-furanolates as key intermediates. ... The first synthesis of nostoclide I and II is reported.