Synthesis of 1, 3-dioxin-4-ones having chiral hydroxyalkyl groups at the 6-position by means of baker's yeast reduction and their uses for epc synthesis
Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Prochiral methyl ketones connected with 6-(4-oxo-1,3-dioxinyl) group directly or through methylene chain (1–3) gave, by treatment with fermenting baker's yeast, the corresponding (S)-alcohols which served as synthons for a variety of enantiomerically pure compounds.
