Synthesis of dinitrophenyltetrapeptides as chromophoric substrates of endoproteinases

…, NY Sokolova, SV Rodin, MA Samartsev

文献索引：Kulikov, S. V.; Sokolova, N. Yu.; Rodin, S. V.; Samartsev, M. A. Chemistry of Natural Compounds, 1983 , vol. 19, # 4 p. 469 - 475 Khimiya Prirodnykh Soedinenii, 1983 , vol. 19, # 4 p. 499 - 504

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被引用次数: 1

摘要

Abstract The synthesis has been performed of ten tetrapeptides of the general formula Dnp- Gly-Gly-X-Arg-OH, where X= Val, Phe, Abu, Asp (OBu t), Asp, Met, D-Phe, Ser, Thr, or Trp. The synthesis was carried out with Dnp-Gly-Gly-ONp, activated esters of protected amino acids, and arginine with an unprotected carboxy group. The coefficients of molar extinction of the tetrapeptides at 660 nm are given. It has been shown that the peptides can be used ...