Tetrahedron letters

A copper-free palladium catalyzed cross coupling reaction of vinyl tosylates with terminal acetylenes

X Fu, S Zhang, J Yin, DP Schumacher

文献索引：Fu, Xiaoyong; Zhang, Shuyi; Yin, Jianguo; Schumacher, Doris P. Tetrahedron Letters, 2002 , vol. 43, # 37 p. 6673 - 6676

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被引用次数: 108

摘要

A copper-free palladium-catalyzed cross coupling of vinyl tosylate (2) and terminal acetylenes was investigated, affording a convenient and efficient method for construction of an sp–sp2 carbon carbon bond. The tosylate (2) derived from 1, 3-cyclohexanedione was reacted with terminal acetylene under the copper-free conditions at ambient temperature, in the presence of palladium acetate and triphenylphosphine, to provide the conjugated en- ...