Abstract Synthesis of 1-alkoxy-or 1-alkylthio-1, 3-bis (azolyl)-2-anylpropan-2-ols is described. The title compounds were examined for their anti-fungal activities in vitro by evaluation of broth dilution MIC values against 3 species of fungi and the inhibitory effect on the pseudomycelium formation by Candida albicans and oral efficacy in vivo against systemic candidiasis in mice.(1R∗, 2R∗)-2-(4-Chlorophenyl)-1-methoxy-1, 3-bis (1, 2, 4- ...