Tetrahedron

Sequencing cross-metathesis and non-metathesis reactions to rapidly access building blocks for synthesis

G Sirasani, T Paul, RB Andrade

文献索引：Sirasani, Gopal; Paul, Tapas; Andrade, Rodrigo B. Tetrahedron, 2011 , vol. 67, # 12 p. 2197 - 2205

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被引用次数: 9

摘要

The olefin cross-metathesis reaction has been sequenced with four common organic transformations in a one-or two-pot manner to rapidly access useful building blocks. Those reactions are:(1) phosphorus-based olefination (eg, Wittig and Horner–Wadsworth– Emmons);(2) hydride reduction;(3) Evans propionate aldol reaction;(4) Brown allyl-and Roush crotyl-boration. The products of these reactions include stereodefined 2, 4- ...