Cembranoids, a 14-membered cyclic diterpene family, have become of interest to synthetic chemists and biologists because of their unusual structures and wide range of biological activities.1 and 2Sinulariol-B 1, sinulariol-D 2, sinularial-A 3 and sinularic acid-A 4 were isolated in 1987 and 1988 from the southern Japan soft coral Sinularia mayi. 3 and 4Their geometrical structures and configurations were confirmed to be 3E, 7E, 11E and 1R, respectively, but the absolute ...
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