Addition of Amines to the Triple Bond in α, α, α-Trichloromethylpropargyl Mesylate: Synthesis of α, α-Dichloromethylenaminones and Preparation of 2-Phenyl-4- …
Addition of amines to the triple bond in α,α,α-trichloromethylpropargyl mesylate to give α,α-dichloromethylenaminones and its use in the preparation of 2-phenyl-4-dichloromethylquinolines in good yields are reported. ... Alkynylation of chloral and bromal with phenylacetylene gave propargyl alcohol 1a and 1b in 95% and 83% yield, respectively, in the presence of ZnCl 2 and Et 3 N according to our previously reported procedure. 10 Initially we envisioned that treatment of the ...
