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Design and synthesis of C6-C8 bridged epothilone A

W Zhan, Y Jiang, PJ Brodie, DGI Kingston…

文献索引:Organic Letters, , vol. 10, # 8 p. 1565 - 1568

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被引用次数: 28

摘要

... Volume: Page: ... Organic Letters. ... For the Suzuki−Miyaura cross coupling, vinyl iodide 5 was prepared from the previously reported aldehyde 17 18b (85% yield, Z/E = 10:1) using the Stork and Zhao olefinationprotocol (Scheme 4). 26 The geometry of the C C was ...