Organic letters

Ligand Effects on Negishi Couplings of Alkenyl Halides

A Krasovskiy, BH Lipshutz

文献索引：Krasovskiy, Arkady; Lipshutz, Bruce H. Organic Letters, 2011 , vol. 13, # 15 p. 3818 - 3821

被引用次数: 34

摘要

Negishi couplings at olefinic centers do not always occur with the anticipated maintenance of stereochemistry. The source of erosion has been traced to the ligand, and a modified method has been developed that solves the stereochemical issue and significantly improves yields of Negishi couplings in general.

~84%

~6%

~17%

详细

~16%

~12%

详细

~12%

详细

~15%

详细

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