Synthesis, physicochemical properties, and biological evaluation of hydroxypyranones and hydroxypyridinones: novel bidentate ligands for cell-labeling

…, MB Hossain, S Rizvi, D van der Helm

文献索引：Ellis, Beverley L.; Duhme, Anne K.; Hider, Robert C.; Hossain, M. Bilayet; Rizvi, Safia; Van Der Helm, Dick Journal of Medicinal Chemistry, 1996 , vol. 39, # 19 p. 3659 - 3670

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被引用次数: 85

摘要

The synthesis of a range of hydroxypyranones and hydroxypyridinones with potential for the chelation of indium (III) is described. The crystal structures of two of the indium complexes are presented. The distribution coefficients of the ligands and the corresponding iron (III), gallium (III), and indium (III) complexes are reported. Good linear relationships between the distribution coefficients of the iron and gallium complexes and iron and indium complexes ...