Potential antihistamine agents: 4-(6, 11-Dihydrodibenzo [b, e] thiepin-11-ylidene)-1-methyltetrahydrothiopyranium iodide and similar sulfonium salts derived from …

…, J Holubek, M Buděšínský, O Matoušová…

文献索引：Polivka, Zdenek; Holubek, Jiri; Budesinsky, Milos; Matousova, Oluse; Svatek, Emil; et al. Collection of Czechoslovak Chemical Communications, 1987 , vol. 52, # 11 p. 2758 - 2774

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被引用次数: 6

摘要

Abstract Thioxanthone, 10, 11-dihydrodibenzo [a, d] cyclohepten-5-one, dibenzo [b, e] thiepin-11 (6H)-one, its 2-methyl derivative, and thieno [2, 3-c]-2-benzothiepin-4 (9H)-one were reacted with 4-tetrahydrothiopyranylmagnesium bromide and the obtained tertiary alcohols IVabc, VIc, and XIX were dehydrated to the olefinic sulfides IXabc, Xc, and XXI. Addition of methyl iodide afforded the title compounds XIabc, XIIc, and XXII. The Grignard ...