A convenient synthesis of 1H-pyrrolo (3, 2-c) quinoline-6, 9-diones and 11H-indolo (3, 2-c) quinoline-1, 4-diones derivatives.

P HELISSEY, H PARROT-LOPEZ, J RENAULT…

文献索引：Helissey; Parrot-Lopez; Renault; Cros Chemical and pharmaceutical bulletin, 1987 , vol. 35, # 9 p. 3547 - 3557

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被引用次数: 15

摘要

8-Methoxy-2, 3, 4-trimethyl-1H-pyrrolo [3, 2-c] quinoline-6, 9-dione (28) and 2-methoxy-6- methyl-7, 8, 9, 10-tetrahydro-11H-indolo [3, 2-c] quinoline-1, 4-dione (31) can be obtained from 4-hydrazino-6-methoxy-2-methyl-5-quinolinamine (21). The synthetic method consists in creating the pyrrole or indole nucleus by applying Fischer's indole synthesis to the hydrazones (22 and 24) to give the amines (23 and 25, respectively). The catalytic ...