Abstract The coupling reaction of corresponding benzene diazonium chlorides with benzoyl acetates IIIa-IIIc yielded intermediates IVa-IVe. Their intramolecular nucleophilic cyclization provided 1-aryl-1, 4-dihydro-4-oxocinnoline-3-carboxylates Va-Ve. Compounds Va, Vb, Vd, and Ve were hydrolyzed to acids VIa-VIc. Treatment of these acids with the respective cyclic amines yielded compounds VIIa-VIIg which were converted to their hydrochlorides. All ...
