Tetrahedron

Sporolide B: synthetic studies

JA Gladding, JP Bacci, SA Shaw, AB Smith

文献索引：Gladding, Jeffery A.; Bacci, James P.; Shaw, Scott A.; Smith III, Amos B. Tetrahedron, 2011 , vol. 67, # 35 p. 6697 - 6706

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被引用次数: 9

摘要

Studies directed toward the synthesis of the architecturally complex marine natural product sporolide B are described. Synthetic analysis suggested advanced hydroquinone and benzodiquinane fragments, which upon elaboration were successfully united via an ester linkage. Macrocyclization studies were then carried out, and although a novel macrocyclization product was obtained, subsequent studies revealed that the tertiary ...