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Tetrahedron Letters

Cu (OTf) 2/Et 3 N-promoted cyclocondensation of activated α-methylene alkenes and nitroolefins: a novel one-pot synthesis of polysubstituted benzenes

W Su, K Ding, Z Chen

文献索引:Su, Weike; Ding, Kai; Chen, Zhiwei Tetrahedron Letters, 2009 , vol. 50, # 6 p. 636 - 639

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被引用次数: 18

摘要

A simple and efficient one-pot synthesis of polyfunctionalized benzenes has been developed via cyclocondensation of activated α-methylene alkenes such as vinyl malononitriles and ethyl vinyl cyanoacetates with nitroolefins using Cu (OTf) 2/Et3N as a novel catalytic system.