Synthesis and characterization of nitroaromatic peptoids: fine tuning peptoid secondary structure through monomer position and functionality

…, R Luechapanichkul, HE Blackwell

文献索引：Fowler, Sarah A.; Luechapanichkul, Rinrada; Blackwell, Helen E. Journal of Organic Chemistry, 2009 , vol. 74, # 4 p. 1440 - 1449

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被引用次数: 30

摘要

N-Substituted glycine oligomers, or peptoids, have emerged as an important class of foldamers for the study of biomolecular interactions and for potential use as therapeutic agents. However, the design of peptoids with well-defined conformations a priori remains a formidable challenge. New approaches are required to address this problem, and the systematic study of the role of individual monomer units in the global peptoid folding ...