Synthesis, biological properties, and molecular modeling investigations of novel 3, 4-diarylpyrazolines as potent and selective CB1 cannabinoid receptor antagonists

JHM Lange, HKAC Coolen…

文献索引：Journal of Medicinal Chemistry, , vol. 47, # 3 p. 627 - 643

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被引用次数: 168

摘要

... Journal of Medicinal Chemistry. ... Introduction. Cannabinoids are present in the Indian hemp Cannabis sativa L. and have been used as medicinal agents for centuries. 1-4 However, only within ... Chemistry. A set of proprietary compounds ...