One??Pot Synthesis of 3??Substituted Isoquinolin??1??(2H)??ones and Fused Isoquinolin??1??(2H)??ones by SRN1 Reactions in DMSO

JF Guastavino, SM Barolo…

文献索引：Guastavino, Javier F.; Barolo, Silvia M.; Rossi, Roberto A. European Journal of Organic Chemistry, 2006 , # 17 p. 3898 - 3902

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被引用次数: 26

摘要

Abstract 3-Substituted isoquinolin-1-(2H)-ones and fused isoquinolin-1-(2H)-ones have been obtained by the photostimulated S RN 1 reactions of 2-iodobenzamide with the enolates of aromatic (acetophenone, 1-(benzo [d][1, 3] dioxol-5-yl) ethanone, 1-and 2- naphthyl methyl ketones, and 2-, 3-, and 4-acetylpyridine), aliphatic (1-adamantyl methyl ketone), and cyclic ketones (1-and 2-indanone, α-and β-tetralone, and 1-benzosuberone) ...