Journal of medicinal chemistry

Synthesis of potential antiradiation agents from 3-substituted 2-oxazolidinones derived from phenol, benzenethiol, and related compounds

RD Elliott, TP Johnston

文献索引：Elliott,R.D.; Johnston,T.P. Journal of Medicinal Chemistry, 1969 , vol. 12, # 2 p. 253 - 257

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被引用次数: 1

摘要

The IIBr cleavage of hubstit iited 2-uxazolidinoncs was effectively: ipplied ill the byntlicsis of h'-substituted and N, S-disubstituted derivatives of 2-aminoethanethiol in which the?; substituent is a 2-phenoxy-,(phenylthio)-,(phenylsulfonyl)-, or (2-pyridy1thio) ethyl or a correspondingly 3-substituted propyl group. h'one of these modifications of the amino group led to radioprotective activity approaching that of the parent compounds. Bmong the thiols, ...