The Journal of Organic Chemistry

DABCO-catalyzed coupling of aldehydes with activated double bonds. 4. Stereoselective synthesis of trisubstituted olefins and terpenoid building blocks via 2-( …

HMR Hoffmann, J Rabe

文献索引：Hoffmann, H. Martin R.; Rabe, Juergen Journal of Organic Chemistry, 1985 , vol. 50, # 20 p. 3849 - 3859

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被引用次数: 150

摘要

A variety of 2-(hydroxyalkyl)-2-propenoic esters 16a-g has been prepared in high yield by DABCO-catalyzed coupling of aldehydes 14a-g with methyl acrylate. The product esters 16a- g are useful building blocks in syntheses which undergo regioselective and 2-selective SN~'reactions with N-bromosuccinimide/dimethyl sulfide and